Cov tshuaj tua kab mob rau Alzheimer's Disease thiab nco tsis tau --- Huperzine Extract
Huperzine A Extract yog dab tsi?
Huperzine extractyog cov nroj tsuag ntuj alkaloid rho tawm los ntawm Huperzia cog Melaleuca. Nws yog ib qho ntuj thiab muaj txiaj ntsig acetylcholinesterase inhibitor. Nws yog lub teeb daj rau dawb crystalline hmoov, soluble hauv methanol thiab ethanol, me ntsis Soluble nyob rau hauv dej, heev fat-soluble, me me molecules tau yooj yim nkag mus rau hauv cov ntshav.
Huperzine A hmoov muaj cov khoom siv roj ntsha siab, tuaj yeem nkag mus rau hauv cov ntshav-hlwb hauv hlwb, muaj zog inhibitory nyhuv ntawm acetylcholinesterase (AchE) ntawm cov koob tshuaj tsawg, thiab nce qib ntawm acetylcholine (Ach) hauv qhov sib txawv synaptic hauv thaj chaw faib khoom. Huperzia serrata nplooj extract tuaj yeem txhawb kev zoo siab ntawm cov neurons, ntxiv dag zog rau kev kawm thiab kev nco muaj peev xwm ntawm lub hlwb, txhim kho kev txawj ntse, txhim kho kev nco thiab ntxiv dag zog rau kev tsim tawm ntawm kev nco. Huperzia serrata hmoov yog ib qho tshuaj zoo raw khoom rau kev kho mob thiab kev loj hlob ntawm senile dementia.
Acetylcholinesterase yog dab tsi?
Acetylcholinesterase yog ib qho enzyme uas decomposes neurotransmitter acetylcholine hauv lub hlwb, thiab yog lub luag haujlwm tseem ceeb rau kev ua haujlwm tseem ceeb ntawm cov neurons hauv lub hlwb thiab cov paj hlwb excitation ntawm lub hauv nruab nrab paj hlwb. Ib lub molecule ntawm acetylcholinesterase tuaj yeem degrade kwv yees li 25, 000 molecules ntawm acetylcholine. Inhibitors ntawm cov enzyme no feem ntau siv rau hauv cov paj hlwb npaj vim tias ntau dhau acetylcholine hauv lub cev tuaj yeem ua rau cov leeg tuag tes tuag taw thiab tuag los ntawm asphyxiation. Cov neeg mob Alzheimer's kab mob feem ntau tsis muaj acetylcholine, vim acetylcholine muaj nuj nqis tseem ceeb hauv lub hlwb lub paj hlwb, kev nco thiab kev kawm muaj peev xwm. Huperzine A extract ntawm Melaleuca tuaj yeem txo cov qib ntawm acetylcholinesterase, tso tawm acetylcholine, txhawb kev ua haujlwm ntawm neurons, thiab zam lub hlwb neurodegeneration.
Huperzine A ua dab tsi? (Huperzia Serrata Extract Benefits)
Huperzine A yog qhov thim rov qab thiab muaj zog cholinesterase inhibitor nrog 99 feem pua kev ua tau zoo hauv kev kho mob myasthenia gravis.
Clinically, huperzine A feem ntau muaj cov teebmeem hauv qab no:
1. Huperzia serrata nplooj ntawv txheem extract yog siv los kho thiab txo kev nco poob rau cov neeg laus thiab cov laus, txhim kho kev nco, pab txo qis kev nco los ntawm kev siv lub hlwb ntau dhau, thiab txhim kho kev kawm thiab kev ua haujlwm zoo;
2. Melaleuca huperzine A yog siv rau kev kho mob ntawm kev nco tsis cuam tshuam nrog neurasthenia;
3. Huperzine extracttuaj yeem kho qhov tsis nco qab los ntawm cov kab mob cerebrovascular;
4. Huperzine A hmoov yog siv los txhim kho senile dementia, pab kho cov neeg mob kev paub, kev nco ua haujlwm thiab txhim kho kev xav;
5. Ntuj huperzine A yog siv los kho myasthenia gravis;
6. Pure huperzine A hmoov muaj qhov pom tseeb los ntawm kev sib koom ua ke, kev paub tsis tshua muaj nuj nqi thiab tsis nco qab cuam tshuam nrog schizophrenia;
7. Huperzine cov hmoov ntau kuj tuaj yeem muaj txiaj ntsig zoo rau kev nco tsis tau cuam tshuam nrog cov kab mob hauv lub hlwb thiab kab mob hauv lub cev.
Huperzine A Extract Puas tuaj yeem kho Alzheimer's?
Huperzine A yog ib qho kev thim rov qab acetylcholinesterase inhibitor. Nws yog siv nyob rau hauv kev kho mob raws li ib tug tshuaj rau kev kho mob ntawm benign nco impairment thiab me me mus rau nruab nrab Alzheimer's kab mob. Nws tuaj yeem txhim kho kev nco ntawm cov neeg mob thiab txhim kho cov tsos mob ntawm Alzheimer's disease.
Cov kev tshawb fawb pharmacological tau pom tias huperzine A extract tuaj yeem tswj hwm feem ntau ntawm cov paj hlwb hauv lub hlwb, txhawb kev tso tawm cov neurotransmitters hauv lub hlwb, thiab tom qab ntawd pab txhim kho Alzheimer's thiab kev txawj ntse. Cov txheej txheem tshwj xeeb ntawm kev ua haujlwm rau kev kho mob Alzheimer's kab mob yog raws li hauv qab no:
1. Raws li ib tug muaj zog thiab zoo acetylcholinesterase inhibitor, huperzia serrata tshuaj ntsuab extract tau yooj yim nkag mus rau hauv nruab nrab paj hlwb los ntawm cov hlab ntsha-hlwb barrier, ua ke nrog acetylcholinesterase, inhibit acetylcholinesterase nyob rau hauv lub hlwb, txo cov decomposition ntawm acetylcholine, thiab txhim kho lub hlwb. Cov concentration ntawm cov acetylcholine sab hauv, uas tswj kev sib kis ntawm cov teeb liab ntawm synapses;
2. Huperzine A nyob rau hauv ntau tuaj yeem tiv thaiv cov dawb radicals, zoo inhibit qhov tsim ntawm cov dawb radicals nyob rau hauv nruab nrab paj hlwb, tiv thaiv oxidation sai thiab aging ntawm paj hlwb, tswj kev ncaj ncees ntawm paj hlwb, thiab tiv thaiv lub hlwb ua haujlwm;
3. Lub ntuj Melaleuca extract muaj qee yam tshuaj tiv thaiv kab mob. Lub hauv paus inflammatory teb tshwm sim los ntawm kev tsis ua hauj lwm ntawm lub cev tiv thaiv kab mob yuav ua rau neuronal puas. Cov kev tshawb fawb tshuaj muaj feem xyuam tau pom tias huperzine A tuaj yeem cuam tshuam kev ua kom muaj zog thiab ua kom cov hlwb hauv lub paj hlwb. Ua kom muaj NF-KB inflammatory dredging collaterals, inhibiting tiam thiab tso tawm ntawm ntau yam inflammatory yam, thiab zoo txhim kho cov mob inflammatory teb ntawm lub paj hlwb;
4. Huperzine A tuaj yeem tiv thaiv cell apoptosis. Ntau tus neuronal cell apoptosis yog lub ntsiab ua rau Alzheimer's kab mob, thiab Huperzine A tuaj yeem inhibit qhov tsim ntawm cov pa oxygen reactive thiab kev ua haujlwm ntawm caspase-3 enzyme hauv neuron cell lub cev, ncua kev pab cuam apoptosis ntawm neurons, txhim kho cov ciaj sia taus ntawm central paj hlwb, thiab alleviate lub degeneration ntawm lub hlwb muaj nuj nqi.
Huperzine A inhibit li cas?
Huperzine extractmuaj kev xaiv inhibitory cuam tshuam rau qhov tseeb cholinesterase, thiab qhov kev siv tshuaj inhibitory yog ntau txhiab npaug ntawm cov cholinesterase cuav. Cov nyhuv inhibitor yog siab dua; nws yooj yim nkag mus rau hauv lub paj hlwb los ntawm cov ntshav-hlwb barrier, thiab muaj kev cuam tshuam hauv nruab nrab thiab peripheral; nws muaj kev nqus zoo thiab digestion cuam tshuam hauv txoj hnyuv. Kev sib piv cov txiaj ntsig ntawm inhibitory kev siv ntawm cov tshuaj sib txawv yog raws li nram no: huperzine A > physostigmine > neostigmine > huperzine B > galantamine > galanin.
Huperzine A extract muaj ib qho kev xaiv inhibitory nyhuv ntawm qhov tseeb cholinesterase, thiab qhov kev siv zog inhibitory yog ntau txhiab zaus ntawm cov cholinesterase cuav. Cov nyhuv inhibitor yog siab dua; nws yooj yim nkag mus rau hauv lub paj hlwb los ntawm cov ntshav-hlwb barrier, thiab muaj kev cuam tshuam hauv nruab nrab thiab peripheral; nws muaj kev nqus zoo thiab digestion cuam tshuam hauv txoj hnyuv. Kev sib piv cov txiaj ntsig ntawm inhibitory kev siv ntawm cov tshuaj sib txawv yog raws li nram no: huperzine A > physostigmine > neostigmine > huperzine B > galantamine > galanin.
Puas yog huperzine A nyab xeeb? (Puas Huperzine A noj tau ntev?)
Tam sim no, tsis muaj kev kho mob tag nrho rau Alzheimer's disease. Txawm tias huperzine A tsuas tuaj yeem txo qis thiab txhim kho cov tsos mob, tab sis tsis tuaj yeem thim rov qab cov qauv ntawm lub paj hlwb. Yog li, huperzine A puas tuaj yeem noj tau ntev?
Cov lus teb yog: Huperzine A extract tuaj yeem noj tau ntev, tab sis cov koob tshuaj yuav tsum tau hloov kho raws li qhov xwm txheej, thiab cov tshuaj tsis zoo yuav tsum tau them rau.
Huperzine serrata tag nrho cov nroj tsuag tuaj yeem nqus tau sai sai tom qab nkag mus rau hauv tib neeg lub cev, thiab nkag mus rau hauv lub hlwb cov hlab ntsha li 3 teev tom qab noj, tab sis cov nyhuv tiag tiag yuav siv sijhawm 6-12 teev kom ncav cuag qhov kawg ntawm cov nyhuv tshuaj; Huperzine A tau tso tawm qeeb qeeb hauv lub cev, thiab lub voj voog metabolic yog txog nws kav 24-36 teev, thiab feem ntau yog tawm los ntawm ob lub raum hauv cov zis tom qab tau metabolized los ntawm lub siab. Vim lub sij hawm ntev ntawm cov metabolism, nws yuav ua rau cov tshuaj tsub zuj zuj tom qab noj ntau ntau, ua rau muaj tshuaj lom. Nws raug pom zoo los ntawm kws kho mob hais tias qhov siab tshaj plaws txhua hnub koob tshuaj yuav tsum tsis pub tshaj 0.45 mg, txwv tsis pub nws yuav ua rau muaj kev phiv tshuaj.
Cov teebmeem ntawm Huperzine A:
Cov kev phiv tshwm sim ntawm huperzine A yog qhov tshwm sim hauv kev kho mob xws li tinnitus, kiv taub hau, mob fasciculation, limb tremor, thiab lwm yam, tab sis lawv feem ntau tuaj yeem zam tau thiab tsis tas yuav tsum tau tso tseg cov tshuaj, thiab qee cov neeg mob yuav ntsib kev tsis zoo xws li mob plab. mob, xeev siab, ntuav, thiab qhov muag tsis pom kev tshwm sim.
Huperzine A yuav tsum tau siv nrog ceev faj hauv pawg hauv qab no:
1. Bronchial hawb pob: siv Huperzine A extract nrog ceev faj, nws yog ib qho yooj yim ua rau tracheal constriction thiab induce asthma;
2. Cov neeg mob uas muaj lub plab zom mov tsis zoo: Huperzine A tuaj yeem ua rau lub plab zom mov, ua rau lub plab hnyuv loj;
3. Cov neeg mob angina pectoris thiab bradycardia: Huperzine A hmoov yuav ua rau lub plawv dhia qeeb thiab ua rau myocardial puas tsuaj;
4. Cov neeg mob lub raum tsis txaus: lub raum yog txoj hauv kev tseem ceeb rau kev tso tawm huperzine A, thiab nws yooj yim ua rau lub raum tsis ua haujlwm;
5. Cov poj niam cev xeeb tub, menyuam yaus thiab cov poj niam pub niam mis yog txwv tsis pub noj huperzine A.
Kuv tuaj yeem yuav Huperzine A qhov twg?
Shaanxi Hongda Phytochemical Co., Ltd. yog Melaleuca extract chaw tsim tshuaj paus thiab huperzine A tsum. Nws tuaj yeem tsim thiab muab cov khoom zoo huperzine A. Nws yog tsim los ntawm nruj raws li GMP cov qauv thiab cov qauv tshuaj, tsis muaj cov khoom siv ntxiv, tuaj yeem kho raws li cov neeg siv khoom xav tau, txais tos los tham!
